The derivation and setting of occupational exposure limits (OELs) is an important component of the risk assessment and risk management of chemicals in different national as well as international processes. On the EU level the harmonisation of airborne exposure limit values is a current issue, because for some substances different exposure limits for workplaces were yielded by occupational safety and health legislation on the one hand and by chemicals legislation on the other hand. Important steps in the process of setting OELs or analogue values are the determination of a point of departure based on adverse effects reported in toxicological studies and the application of assessment factors to bridge data gaps (regarding studies with different
exposure duration, differences between species and variability in sensitivity between humans).
The objective of this project was to analyse and disclose the differences between the current methods for deriving exposure limits and the resulting differences in protection levels. To achieve this,
Further, we investigated important instruments and methods for deriving exposure limits
The overarching aim was to develop a common understanding of the necessary methodological steps in the setting of exposure limits and in this way to support harmonisation of the derivation of occupational exposure limits in the EU.
K. Schneider, M. Dilger, E. Kaiser, F. Kalberlah, W. Wosniok:
Derivation of occupational exposure limits for airborne chemicals - Comparison of methods and protection levels.
1. edition. Dortmund: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin 2022. pages 876, Project number: F 2437, PDF file, DOI: 10.21934/baua:bericht20220112