Validation of models for the initial estimation of occupational exposure (Tier 1) in the chemical safety assessment under REACH

  • Project number: F 2303
  • Institution: Institute of Occupational Medicine (IOM), Edinburgh / Fraunhofer ITEM
  • Status: Completed Project

Description:

The Tier 1 models (ECETOC TRA, Stoffenmanager, EMKG-Expo-Tool) recommended in European Chemicals Agency (ECHA) guidance document R14 for occupational exposure assessment towards hazardous substances in the context of REACH are validated only to a limited extent regarding their scientific performance. A small scale comparison of measured data with the predicted exposure levels (done by the model owners) is available for Stoffenmanager and EMKG-Expo-Tool. In this project, principles for the validation of the exposure models that are listed in R14 will be analysed and further developed in cooperation with international partners. By means of a conceptual analysis of the respective scientific assumptions, a comparison of the calculated output of the models with measurement data on a large scale, and an operational analysis (regarding operating comfort, errors etc.) the suitability of the models for different exposure scenarios will be investigated.

Publications

Understanding the Limitations and Application of Occupational Exposure Models in A Reach Context

Publishing year: 2023

Suchergebnis_Format Article

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Validity of Tier 1 Modelling Tools and Impacts on Exposure Assessments within REACH Registrations - ETEAM Project, Validation Studies and Consequences

Publishing year: 2020

Suchergebnis_Format Article

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Further stratification of the ETEAM study results

Publishing year: 2016

Suchergebnis_Format baua: Report

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Evaluation of Tier 1 Exposure Assessment Models under REACH (eteam) Project - Substudy Report on Gathering of Background Information and Conceptual Evaluation

Publishing year: 2015

Suchergebnis_Format Report

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Evaluation of Tier 1 Exposure Assessment Models under REACH (eteam) Project - Substudy Report on External Validation Exercise

Publishing year: 2015

Suchergebnis_Format Report

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Evaluation of Tier 1 Exposure Assessment Models under REACH (eteam) Project - Substudy Report on User-Friendliness of Tier 1 Exposure Assessment Tools under REACH

Publishing year: 2015

Suchergebnis_Format Report

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Evaluation of Tier 1 Exposure Assessment Models under REACH (eteam) Project - Substudy Report on Between-User Reliability Exercise (BURE) and Workshop

Publishing year: 2015

Suchergebnis_Format Report

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Evaluation of Tier 1 Exposure Assessment Models under REACH (eteam) Project - Substudy Report on Uncertainty of Tier 1 Models

Publishing year: 2015

Suchergebnis_Format Report

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Evaluation of Tier 1 Exposure Assessment Models under REACH (eteam) Project - Final Overall Project Summary Report

Publishing year: 2015

Suchergebnis_Format Report

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Evaluation of Exposure Assessment Tools under REACH: Part I - Tier 1 Tools

Publishing year: 2019

Suchergebnis_Format Article

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Between-User reliability of Tier 1 Exposure assessment tools used under REACH

Publishing year: 2017

Suchergebnis_Format Article

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Evaluation of tier one exposure assessment models (ETEAM): Project overview and methods

Publishing year: 2017

Suchergebnis_Format Article

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Validation of Lower Tier Exposure Tools Used for REACH: Comparison of Tools Estimates With Available Exposure Measurements

Publishing year: 2017

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Evaluation of Tier 1 Exposure Assessment Models used under REACH (ETEAM Project): Background and Aims of the ETEAM Project

Publishing year: 2015

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Further Information

Contact

Unit 4.I.4 "Exposure Assessment, Exposure Science"

Phone: +49 231 9071-1971
Fax: +49 231 9071-2070