This project examines the cause for the differential dustiness of different nanocarbons. According to the current toxicological understanding, the factors 'morphology' and 'rigidity' are of fundamental importance in the evaluation of possible cancer risks by respirable, biopersistent fibres from innovative materials (such as carbon nanotubes and fibres). Three methods of activity-based analysis of dustiness will be used to determine the dusting propensity of various forms of nanoscale carbon compounds. Results will be correlated with a range of morphological characteristics in order to test whether there is a relationship between the morphologic characteristics of a material and its dusting propensity. Further, it will be analysed whether dusting propensity is a function of the rigidity of a material. The latter objective overlaps with the focus of another BAuA research project (F 2365 - Development of an enforceable test method for determination of the rigidity of respirable biopersistent fibres). Results from both projects are the basis for a systematic evaluation of completed or yet to be initiated animal studies on the relationship of fibre geometry, biopersistence and rigidity. Furthermore, results will be of importance for the development of safe-by-design nanocarbon fibres.
Unit 4.5 "Particulate Hazardous Substances, Advanced Materials"