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Use of trichloroethylene in closed systems - Biomonitoring of operators and bystanders

Project number: F 2379 Institution: Federal Institute for Occupational Safety and Health (BAuA) Status: Ongoing Project Planned end: 2022-06-30


Trichloroethylene (TRI) is used, among others, as a solvent in industrial parts cleaning processes and as extraction solvent for bitumen in asphalt laboratories.
The application of TRI requires an authorisation in accordance with REACH.

Because of its high volatility closed systems for TRI are challenging. Even small leakages can lead to workers' exposure to TRI.

Against this background, the current TRI levels in workers will be surveyed by biological monitoring. Therefore, trichloroacetic acid, a metabolite of TRI, in urine and TRI in exhaled air will be determined. The latter is used for further development and testing of a BAuA method for usage of exhaled breath in routine biological monitoring. In addition, workplace air monitoring of TRI will be conducted.

The measurement data will be independent of applicants and will improve amongst others the data basis for future decisions in relation to applications of authorisation in accordance with REACH.


Unit 4.2 "Health Surveillance, Biological Monitoring"

Phone: +49 231 9071-1971 Fax: +49 231 9071-2070

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