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Depression, burnout and cognitive deficits - studies on the influence of work- related and individual determinants

Project number: F 2318 Institution: Duke University Medical Center / Charite Universitätsmedizin Berlin / IfADo, Leibniz-Institut für Arbeitsforschung Status: Ongoing Project Planned end: 2017-09-30


The relationship between work and mental disorders will be examined in the proposed research project. This study will focus on the influence of psychological stress on mental disorders which are most likely related to work issues: depression symptoms, burnout and cognitive impairements.

The following topics will be tackled in a project consortium:

  1. Work and individual-related determinants of vulnerability to burnout and depression (BAuA)
  2. Relationship between psychosocial stress at work, depression symptoms and cognitive deficits (Duke University, Department of Psychiatry and Behavioral Sciences, USA) and
  3. Depression, work-related factors and central nervous information processing (IfADo)

In the sub-projects, both identical questions (eg influence of work-related factors on depressive symptoms and burnout; moderating and mediating influences on the strength of this relation) as well as specific issues according to the specifics of the focal points of the 3 sub-projects (eg TP 1: causes of interindividual differences of vulnerability to burnout and depression, TP 2: Relationships between mental disorders and cognitive impairments, TP 3: Relationship between mental disorders, information processing and the reward system of the brain).

The expected results on the effects of specific work-related factors on the development of depressive disorders and burnout as well as possible compensation factors can be used for the screening of both depression risks and risk individuals. Furthermore, important insights for the development of intervention concepts for an evidence-based policy advice for the prevention of mental disorders can be expected.


Unit 3.4 "Mental Health and Cognitive Capacity"

Phone: +49 231 9071-2071 Fax: +49 231 9071-2070